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17). Human data regarding e-cig effects for longer use are needed. To better understand health effects of e-cigs, focusing on the solvent carriers e-liquid constituents, we conducted a pilot clinical trial of never-smokers randomized to nicotine- and flavor-free e-cigs, examining lung inflammation and gene expression. MATERIALS AND METHODS
Jan 01, 2019 · From the time of their introduction, the popularity of e-cigarettes (electronic nicotine delivery systems) has been rising. This trend may reflect the general belief that e-cigarettes are a less hazardous alternative to combustible cigarettes. However, the potential cancer-related effects of increased activation of the sympathoadrenal system induced by the inhalation of nicotine, the primary ...
Feb 01, 2020 · Available preclinical data indicate that activation of the sympathetic nervous system by nicotine inhaled from e-cigarettes may stimulate cancer development and growth by several mechanisms. This issue might be especially important for oncological patients as they may have the misconception that compared with combustible cigarettes, e-cigarettes represent a risk-free alternative.
01/11/2011 · The premise of long-term NRT use is that it would prevent smoking relapse, and the risks would be limited to maintaining nicotine addiction, but without the adverse consequences of continued smoking, such as increased lung cancer risk. Like the consideration of other long-term medications, on face value it is a simple risk–benefits equation.
Jan 01, 2019 · Introduction. Although lung cancer mortality has declined consistently in the United States, it still accounts for over 25% of all cancer-related deaths (); thus, further decreasing lung cancer is a major public health priority ().Research reported in the 1950s and 1960s showed that cigarette smoking causes 80%–90% of lung cancers and prompted increases in smoking cessation and decreases in ...
01/12/2017 · Introduction: Use of non-cigarette tobacco products such as cigars and pipe has been increasing, even though these products entail exposure to similar carcinogens to those in cigarettes. More research is needed to explore the risk of these products to guide cancer prevention efforts. Methods: To measure the association between cigars and/or pipe smoking, and cancer incidence in …